Trump called Wiles "one of my most trusted advisors" and said she "has done an outstanding job." His post gave no reason for the change. Wiles wrote on X that "Today is my last day as White House Chief of Staff," calling it "the honor of a lifetime" and pointing to "securing our border and cutting taxes." She is reported to have submitted her resignation on Thursday night.

The shake-up comes days after Tuesday's midterm elections, in which Republicans lost control of Congress. Accounts of why she is leaving differ. One says Trump has been blaming her for the party's losses. Another points to friction between Wiles and Trump aide James Blair over how the MAGA Inc. super PAC was run, along with weak Republican polling before the vote. Trump had publicly defended her position as recently as October 16. Separately, Wiles is said to have tried to temper the mass-deportation push that Miller champions.

Miller is one of the main architects of the administration's hard-line immigration policies. He joined Trump's circle as a speechwriter on the 2016 campaign, after working as an aide to Jeff Sessions, then a senator and later attorney general. He is a frequent critic of Democrats on social media and is involved in the administration's anti-fraud task force. He is expected to take a more combative approach toward the incoming Democratic-controlled Congress. His promotion follows criticism from human rights groups and political opponents of Immigration and Customs Enforcement raids in American neighborhoods since Trump's return to office.

Wiles ran Trump's 2024 campaign and became chief of staff after he won. Trump noted that she also co-chaired his 2016 and 2020 campaigns. Her earlier work included stints for President Ronald Reagan and for Florida politicians such as Rick Scott and Ron DeSantis. She is the daughter of the late NFL broadcaster Pat Summerall. In December 2025 she gave Vanity Fair an interview with candid remarks about Trump and other officials that caused a brief public controversy. In March she disclosed a breast cancer diagnosis, and in September she announced it had resolved after surgery and chemotherapy.

Wiles is the latest of several prominent women to leave the administration this year. Attorney General Pam Bondi, Homeland Security Secretary Kristi Noem, Labor Secretary Lori Chavez-DeRemer and Director of National Intelligence Tulsi Gabbard have all been replaced by men.